It is difficult to establish in the different series what number of patients would fit within this definition. In some series, Up to 50% of patients have some degree of work disability within the first 10 years of arthritis evolution, while in others, such as in a Scandinavian study that reinforces the idea of a better current prognosis of the AR, patients with high degrees of disability do not reach 10% after a follow up of up to 16 years.
However, it is common knowledge that the clinical course of RA varies from one patient to another. While some patients achieve a satisfactory control of the disease, and even episodes of complete remission Keto Viante, in others the disease has a progressive and disabling course. In a Dutch series of women with RA followed up for a period of 6 years, the authors conclude that approximately half would follow one or the other course.
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